Therapeutic AreaFormulary ChoicesCost for 28
(unless otherwise stated)
Rationale for decision / comments
6.2 Thyroid and anti-thyroid drugs
Thyroid hormonesLevothyroxine25mcg tablets: £2.85
50mcg tablets: £1.65
100mcg tablets: £1.65
100micrograms/5ml oral
solution sugar free: £162.92 (100ml)
Monitoring requirements are for TFTs annually


Liquid is lactose free but see below

Liothyronine (T3) is classified as not recommended for primary care initiation and considered red when consultant requested
Levothyroxine
Lactose free (Teva)
12.5mcg tablets: £12.75
25mcg tablets: £2.35
50mcg tablets: £1.14
75mcg tablets; £2.28
100mcg tablets: £1.14
Suitable as an alternative to more expensive liquid for lactose intolerant patients
1x75mcg is more cost effective than 1x50mcg and 1x25mcg plus better compliance
12.5mcg strength is useful for fine tuning dose
Anti-thyroid hormonesCarbimazole5mg tablets: £68.12 (100)
20mg tablets: £178.89 (100)
New patients should be counselled regarding warning signs of haematological toxicity.
Monitoring requirements are for FBC, LFTS and TFTs annually
Propylthiouracil50mg tablets: £58.04 (56)Propylthiouracil is included only for patients intolerant to Carbimazole. Monitoring requirements are for FBC, LFTS and TFTs annually

NB. Under no circumstances should Carbimazole and Propylthiouracil be combined.