Therapeutic AreaFormulary ChoicesCost for 28
(unless otherwise stated)
Rationale for decision / comments
Premonitory stage (pre-hospital)Midazolam Buccal solution

as Buccolam®
10mg/2ml
Pre-filled syringes
2.5mg/0.5ml (yellow label), 4=£82.00.
5mg/1ml (blue label), 4=£85.50.
7.5mg/1.5ml (purple label), 4=£89.00.
10mg/2ml (orange label), 4=£91.50.
Licensed in patients 18yrs and under.



There may be a risk if existing patients are changed from Epistatus® or other unlicensed specials to Buccolam unless there has been clear communication and training for the carer of the different strengths available
As Epistatus®
10mg/1ml pre-filled oral syringe
£45.76
Epistatus® is licensed for use in the treatment of prolonged, acute convulsive seizures in children and adolescents aged 10 to less than 18 years, who have been diagnosed with epilepsy. Buccal midazolam is recommended by NICE for the management of prolonged acute convulsive seizures, and is preferred by most patients and carers compared to the administration of rectal diazepam.
Diazepam 10−20 mg given rectally