Therapeutic AreaFormulary ChoicesCost for 28
(unless otherwise stated)
Rationale for decision / comments
4.5.1 Drugs used in the treatment of obesity
Lipid absorption inhibitorsOrlistat120mg: £18.44 (84)Only to be prescribed in line with NICE guidance:
• BMI > 30kg/m2 or > 28kg/m2 where other risk factors e.g. type 2 DM, hypertension or hypercholesterolaemia
• for patients who have lost ≥ 2.5kg by dietary control and increased physical activity during previous month
• only for individuals between 18 and 75 years
• arrangements should exist for primary care staff (mostly practice nurses) supported by community dieticians to offer advice, support and counselling on diet, physical activity and behavioural strategies
• treatment should continue beyond 3 months only if weight loss of >5% from start of treatment
• treatment should continue beyond 6 months only if weight loss is > 10% from start of treatment
• treatment should not usually continue beyond one year and never beyond two years