Therapeutic AreaFormulary ChoicesCost for 28
(unless otherwise stated)
Rationale for decision / comments
Cardiac glycosidesDigoxin62.5mcg tablets: £2.03
125mcg tablets: £2.10
250mcg tablets: £2.04
Digoxin is included in the formulary for use:
Atrial fibrillation: but not paroxysmal AF
Heart failure: where symptoms persist (due to reduced ejection fraction) despite optimum therapy including ACEIs, B-Blockers and diuretics.
U&Es should be checked at least 6-monthly, or when drug treatment is changed. Monitoring serum potassium is particularly important in patients’ taking digoxin or an aldosterone antagonist. A serum digoxin level should be measured within 8-12 hours of the latest dose only if toxicity or non-adherence is suspected.
Doses of greater than 250mcg per day in adults and greater than 125mcg in patients over 70years should rarely be seen.